I kekahi lā, ua loaʻa iā Ronit (ʻaʻole kona inoa maoli) nā ʻeha ʻōpū, ka hanu pōkole a me ka luhi, a ua hele ʻo ia i ke kauka no nā hoʻāʻo koko. Eia naʻe, ʻaʻole ʻo ia i manaʻo e hoʻouna ʻia ʻo ia i ka haukapila no ka dialysis ma muli o ka hāʻule nui o ka puʻupaʻa.
ʻOiaʻiʻo, ʻaʻole ʻo ia i manaʻo ua hana ʻia kēia mau mea a pau ma muli o kona hoʻopololei ʻana i kona lauoho i ka lā ma mua.
E like me Ronit, ua hoʻokipa ʻia he 26 mau wahine ma ʻIseraʻela, ʻo ka awelika he hoʻokahi wahine i kēlā me kēia mahina, no ka hāʻule nui ʻana o nā puʻupaʻa ma hope o nā lāʻau hoʻopololei lauoho.
Me he mea lā hiki i kekahi o kēia mau wahine ke ho'ōla iā lākou iho. Eia nō naʻe, pono kekahi i ka mālama ʻana i ka dialysis.
Wahi a kekahi, mai loko mai o nā tausani o nā wāhine ma ʻIseraʻela e hoʻopololei i ko lākou lauoho i kēlā me kēia makahiki, "26 wale nō" ka poʻe i loaʻa i ka hāʻule ʻana o nā puʻupaʻa.
I kēia, ke kuhikuhi aku nei au he mea koʻikoʻi loa ka hāʻule ʻana o nā puʻupaʻa e pono ai ka dialysis a he mea hoʻoweliweli hoʻi i ke ola.
E haʻi aku nā mea maʻi iā ʻoe ʻaʻole lākou makemake i kekahi e ʻike i ka trauma lapaʻau. He kumukūʻai kēia ʻaʻole pono e uku ʻia e kekahi no kahi kaʻina hana hoʻonani maʻalahi.
I nā makahiki 2000, ua hōʻike mua ʻia nā hōʻailona mai nā mea hoʻopololei lauoho i loaʻa ka formalin. ʻO ke kumu nui o kēia, ʻo ia ka uahi i hanu ʻia e ka mea hoʻonaninani lauoho i ka wā o ke kaʻina hana hoʻopololei lauoho.
ʻO kēia mau hōʻailona e komo pū ana me ka huhū o nā maka, nā pilikia hanu, nā ʻulaʻula o ka helehelena, ka pōkole o ka hanu, a me ka edema pulmonary.
Akā ʻoiai ʻaʻole i loaʻa ka formalin i nā lāʻau hoʻopololei lauoho hou, aia kekahi mea ʻē aʻe i loko o lākou: ka waikawa glyoxylic.
Hoʻopili ʻia kēia waikawa ma o ke poʻo i hoʻopiha nui ʻia e ke koko. Ke komo i loko o ke koko, ua wāwahi ʻia ka glyoxylate i loko o ka waikawa oxalic a me ka calcium oxalate, kahi e komo hou ai i ke koko a haʻalele i ke kino ma o nā puʻupaʻa i loko o ka mimi.
ʻAʻole ia he mea maʻamau ʻole i loko ona iho, hele nā ​​​​kānaka a pau i ia mea i kekahi ʻano, a ʻaʻohe mea ʻino. Akā i ka wā e hōʻike ʻia ai i nā nui kiʻekiʻe loa o ka waikawa glyoxylic, hiki ke hana i ka lāʻau make oxalic acid, e alakaʻi ai i ka hāʻule ʻana o nā puʻupaʻa.
Ua loaʻa nā waihona calcium oxalate i loko o nā pūnaewele puʻupaʻa i ka wā o nā biopsies puʻupaʻa o nā wahine i loaʻa ka hāʻule ʻana o ka puʻupaʻa ma hope o ka hoʻopololei ʻana i ko lākou lauoho.
I ka makahiki 2021, ua hoʻāʻo kekahi kaikamahine ʻekolu makahiki e inu i ka mea hoʻopololei lauoho. Ua hoʻāʻo wale ʻo ia a ʻaʻole i moni maoli no ka mea he ʻawaʻawa kona ʻono, akā ua hoʻolilo ia i ke kaikamahine i moni iki i loko o kona waha. ʻO ka hopena, he hāʻule nui o nā puʻupaʻa e pono ai ka dialysis, ʻaʻole ka make.
Ma hope o kēia hanana, ua pāpā ke Kuhina Ola i ka hoʻopuka ʻana i nā laikini no nā huahana mālama lauoho pololei a pau i loaʻa ka waikawa glyoxylic me ka pH ma lalo o 4.
Akā ʻo kekahi pilikia ʻē aʻe, ʻaʻole hilinaʻi mau ʻia a pololei loa paha ka ʻike ma nā lepili o nā huahana lauoho pololei. I ka makahiki 2010, ua kapa ʻia kahi huahana Ohio ʻaʻohe formalin, akā aia maoli he 8.5% formalin. I ka makahiki 2022, ua ʻōlelo ʻo ʻIseraʻela ʻaʻohe formalin ka huahana a aia wale nō he 2% glyoxylic acid, akā aia maoli he 3,082 ppm formalin a me 26.8% glyoxylic acid.
ʻO ka mea hoihoi, koe wale nō ʻelua mau hihia o ka oxalic acidosis ma ʻAigupita, ʻo nā hihia honua āpau o ka oxalic acidosis mai ʻIseraʻela mai.
He ʻokoʻa anei ka metabolism o ke akepaʻa i loko o nā wahine ma "ʻIseraʻela" mai ke koena o ka honua? He "palaualelo" iki anei ka gene glyoxylic acid i loko o nā wahine ʻIseraʻela? Aia kekahi pilina ma waena o nā waihona calcium oxalate a me ka laha o ka hyperoxaluria? Hiki ke hāʻawi ʻia i kēia mau maʻi i ka lāʻau like me ka poʻe me ke ʻano 3 hyperoxaluria?
Ke noiʻi ʻia nei kēia mau nīnau a ʻaʻole mākou e ʻike i nā pane no nā makahiki he nui e hiki mai ana. A hiki i kēlā manawa, ʻaʻole pono mākou e ʻae i kekahi wahine ma ʻIseraʻela e hoʻoweliweli i kona olakino.
Eia kekahi, inā makemake ʻoe e hoʻopololei i kou lauoho, aia kekahi mau huahana palekana ʻē aʻe ma ka mākeke i nele i ka waikawa glyoxylic a he laikini kūpono mai ke Keʻena Ola.