I kekahi lā, ua hoʻomaka ʻo Ronit (ʻaʻole kona inoa maoli) e ʻeha i ka ʻōpū, ka hanu pōkole a me ka luhi, a ua hele ʻo ia i ke kauka no kahi hoʻāʻo koko. Eia naʻe, ʻaʻole ʻo ia i manaʻo e hoʻouna ʻia ʻo ia i ka haukapila no ka dialysis ma muli o ka hāʻule nui o ka puʻupaʻa.
ʻOiaʻiʻo, ʻaʻole ʻo ia i manaʻo ua hana ʻia kēia mau mea a pau e ka mea i hoʻopololei ai ʻo ia i kona lauoho i ka lā ma mua.
E like me Ronit, ua hoʻokipa ʻia he 26 mau wahine ma ʻIseraʻela (he awelika o hoʻokahi i kēlā me kēia mahina) i ka haukapila no ka hāʻule nui ʻana o nā puʻupaʻa ma hope o ke kaʻina hana hoʻopololei lauoho.
Me he mea lā hiki i kekahi o kēia mau wahine ke ho'ōla iā lākou iho. Eia nō naʻe, pono kekahi i ka mālama ʻana i ka dialysis.
Wahi a kekahi, ma waena o nā tausani o nā wāhine ma ʻIseraʻela e hoʻopololei ana i ko lākou lauoho i kēlā me kēia makahiki, "26 wale nō" e loaʻa ana i ka hāʻule ʻana o ka puʻupaʻa. Hāʻule ka puʻupaʻa (kiʻi). (Puna: Wikimedia Commons)
I ka pane ʻana, ua kuhikuhi aku au he mea koʻikoʻi loa ka hāʻule ʻana o nā puʻupaʻa e pono ai ka dialysis a he mea hoʻoweliweli hoʻi i ke ola.
E haʻi aku nā mea maʻi iā ʻoe ʻaʻole lākou makemake i kahi ʻeha olakino i kekahi. He kumukūʻai kēia ʻaʻole pono kekahi e uku no kahi hana hoʻonani maʻalahi.
I nā makahiki 2000, ua hoʻomaka mua nā hōʻike o nā hōʻailona i hoʻokumu ʻia e nā mea hoʻopololei lauoho i loaʻa ka formaldehyde. ʻO ke kumu nui o kēia ma muli o ka hanu ʻana o ka mea hana lauoho i ka uahi i ka wā o ke kaʻina hana hoʻopololei.
ʻO kēia mau hōʻailona e komo pū ana me ka huhū o nā maka, nā pilikia hanu, ka ʻulaʻula o ka maka, ka pōkole o ka hanu, a me ka edema pulmonary.
Akā ʻoiai ʻaʻole i loaʻa ka formaldehyde i nā lāʻau hoʻopololei lauoho hou, aia kekahi mea ʻē aʻe i loko o lākou: ka waikawa glyoxylic.
Hoʻopili ʻia kēia waikawa ma o ke poʻo, kahi i waiwai i nā kīʻaha koko. Ke komo i loko o ke kahe koko, wāwahi ka waikawa glyoxylic i ka waikawa oxalic a me ka calcium oxalate, kahi e komo hou ai i ke kahe koko a haʻalele i ke kino ma o nā puʻupaʻa ma ke ʻano he ʻāpana o ka mimi.
ʻAʻole kēia he mea maʻamau ʻole, hele nā ​​​​kānaka a pau i kēia kaʻina hana i kekahi ʻano a ʻaʻohe mea ʻino. Akā i ka wā e hōʻike ʻia ai i nā nui kiʻekiʻe loa o ka waikawa glyoxylic, hiki ke hana ʻia ka oxalic acidosis, e alakaʻi ana i ka hāʻule ʻana o nā puʻupaʻa.
I ka wā o nā biopsies puʻupaʻa o nā wāhine i loaʻa ka hāʻule ʻana o ka puʻupaʻa ma hope o ka hoʻopololei ʻana i ko lākou lauoho, ua loaʻa nā waihona o ka calcium oxalate i loko o nā pūnaewele puʻupaʻa.
I ka makahiki 2021, ua hoʻāʻo kekahi kaikamahine ʻekolu makahiki e inu i kahi huahana hoʻopololei lauoho. Ua hoʻāʻo wale ʻo ia a ʻaʻole i moni, no ka mea, he ʻawaʻawa loa kona ʻono, akā ʻo ka hopena, ua komo kahi liʻiliʻi loa i loko o kona waha. ʻO ka hopena, he hāʻule nui wale nō ia o nā puʻupaʻa e pono ai ka dialysis, ʻaʻole ka make.
Ma hope o kēia hanana, ua pāpā ke Kuhina Ola i ka hoʻopuka ʻana i nā laikini no nā huahana hoʻopololei lauoho a pau i loaʻa ka waikawa glyoxylic a he waiwai pH ma lalo o 4.
Akā ʻo kekahi pilikia ʻē aʻe, ʻaʻole hilinaʻi mau ʻia a pololei loa ka ʻike ma nā lepili o nā huahana hoʻopololei lauoho. I ka makahiki 2010, ua kapa ʻia kahi huahana ma Ohio he formaldehyde-free, akā aia maoli he 8.5 pakeneka formaldehyde. I ka makahiki 2022, ua ʻōlelo kekahi huahana ʻIseraʻela he formaldehyde-free a loaʻa wale nō he 2% glyoxylic acid, akā aia maoli he 3,082 ppm formaldehyde a me 26.8% glyoxylic acid.
ʻO ka mea hoihoi, koe wale nō ʻelua mau hihia o ka oxalic acidosis ma ʻAigupita, ʻo nā hihia honua āpau o ka oxalic acidosis i puka mai mai ʻIseraʻela mai.
He ʻokoʻa anei ka metabolism o ke akepaʻa i nā wahine ʻIseraʻela mai nā mea e hana nei a puni ka honua? He "palaualelo" iki anei nā genes o nā wahine ʻIseraʻela e wāwahi ana i ka waikawa glyoxylic? Aia kekahi pilina ma waena o nā waihona calcium oxalate a me ka laha ʻana o ka maʻi genetic hyperoxaluria? Hiki ke hāʻawi ʻia i kēia mau maʻi i ka lāʻau like me nā maʻi me ka hyperoxaluria type 3?
Ke aʻo ʻia nei kēia mau nīnau, a ʻaʻole mākou e ʻike i nā pane no nā makahiki he nui. A hiki i kēlā manawa, ʻaʻole pono mākou e ʻae i kekahi wahine ma ʻIseraʻela e hoʻoweliweli i kona olakino.
Eia kekahi, inā makemake ʻoe e hoʻopololei i kou lauoho, aia kekahi mau huahana palekana ʻē aʻe ma ka mākeke ʻaʻohe ona waikawa glyoxylic a ua laikini ʻia e ke Kuhina Ola. E kōkua kēia iā ʻoe e mālama i ka lauoho pololei a me ke kino olakino. No ka mea, ua ʻike mākou a pau e puka mai ana ka nani maoli mai loko mai.