Ua ʻōlelo ʻo NICE no ka manawa mua i kahi lāʻau lapaʻau hou e hiki ke kōkua i nā pēpē, nā keiki a me nā ʻōpio e hana ʻia ana i ka lāʻau lapaʻau maʻi kanesa e pale aku i ka nalowale o ka lohe.
He lāʻau chemotherapy ikaika ʻo Cisplatin i hoʻohana nui ʻia e mālama i nā ʻano maʻi kanesa o nā kamaliʻi. I ka hala ʻana o ka manawa, hiki i ka cisplatin ke hōʻiliʻili i loko o ka pepeiao o loko a hoʻoulu i ka mumū a me ka hōʻino i ʻike ʻia ʻo ototoxicity, ʻo ia kekahi kumu o ka nalowale o ka lohe.
Paipai nā ʻōlelo paipai hope loa i ka hoʻohana ʻana i ka sodium thiosulfate anhydrous, i ʻike ʻia hoʻi ʻo Pedmarqsi a hana ʻia e Norgine, e pale aku i ka nalowale o ka lohe i hoʻokumu ʻia e ka chemotherapy cisplatin i nā keiki mai 1 mahina a 17 mau makahiki me nā puʻupuʻu paʻa i laha ʻole i nā ʻāpana ʻē aʻe o ke kino.
Ma kahi o 60% o nā keiki i mālama ʻia me cisplatin e loaʻa i ka nalowale o ka lohe mau loa, me 283 mau hihia hou o ka nalowale o ka lohe ototoxic i ʻike ʻia i nā keiki ma lalo o 18 mau makahiki ma ʻEnelani ma waena o 2022 a me 2023.
ʻO ka lāʻau lapaʻau, i hāʻawi ʻia ma ke ʻano he infusion e ke kahu maʻi a kauka paha, hana ma ka hoʻopaʻa ʻana i ka cisplatin i lawe ʻole ʻia e nā cell a pale i kāna hana, a laila e pale ana i ka hōʻino ʻana i nā cell pepeiao. ʻAʻole hoʻopilikia ka hoʻohana ʻana i ka sodium thiosulfate anhydrous i ka pono o ka chemotherapy cisplatin.
Ua manaʻo ʻia i ka makahiki mua o ka ʻōlelo aʻoaʻo no ka hoʻohana ʻana i ka sodium thiosulfate anhydrous, ma kahi o 60 miliona mau keiki a me nā ʻōpio ma ʻEnelani e kūpono e loaʻa i ka lāʻau lapaʻau.
Hiki i ka nalowale o ka lohe ma muli o ka mālama ʻana i ka maʻi kanesa ke loaʻa ka hopena weliweli i nā keiki a me ko lākou mau ʻohana, no laila hauʻoli mākou e hiki ke paipai aku i kēia koho lapaʻau hou.
ʻO kēia ka lāʻau lapaʻau mua i hōʻoia ʻia e pale a hōʻemi i nā hopena o ka nalowale o ka lohe a he hopena nui ia i ke ola o nā keiki a me nā ʻōpio.
Ua hoʻomau ʻo Helen: "ʻO kā mākou ʻōlelo aʻoaʻo no kēia lāʻau lapaʻau hou e hōʻike ana i ka hoʻokō ʻana o NICE i ka nānā ʻana i nā mea nui loa: ka hāʻawi ʻana i ka mālama maikaʻi loa i nā maʻi me ka wikiwiki a me ka hōʻoia ʻana i ka waiwai maikaʻi no ke kālā no ka mea ʻauhau."
Ua hōʻike ʻia nā ʻikepili mai ʻelua mau hoʻokolohua lapaʻau ua aneane hapalua ka nui o ka nalowale o ka lohe i nā keiki i loaʻa i ka chemotherapy cisplatin. Ua ʻike ʻia kekahi hoʻokolohua lapaʻau he 32.7% ka nui o ka nalowale o ka lohe i nā keiki i loaʻa i ka chemotherapy cisplatin i ukali ʻia e ka sodium thiosulfate anhydrous, ke hoʻohālikelike ʻia me ka 63% o ka nui o ka nalowale o ka lohe i nā keiki i loaʻa i ka chemotherapy cisplatin wale nō.
Ma kekahi noiʻi ʻē aʻe, 56.4% o nā keiki i loaʻa iā cisplatin wale nō i loaʻa ka nalowale o ka lohe, hoʻohālikelike ʻia me 28.6% o nā keiki i loaʻa iā cisplatin a ukali ʻia e ka sodium thiosulfate anhydrous.
Ua hōʻike pū nā hoʻokolohua inā loaʻa i nā keiki ka nalowale o ka lohe, ʻaʻole ia he koʻikoʻi nui i ka poʻe i hoʻohana i ka sodium thiosulfate anhydrous.
Ua haʻi aku nā mākua i kahi kōmike NICE kūʻokoʻa inā loaʻa ka nalowale o ka lohe ma muli o ka chemotherapy cisplatin, hiki iā ia ke hoʻopilikia i ka ulu ʻana o ka ʻōlelo a me ka ʻōlelo, a me ka hana ʻana ma ke kula a ma ka home.
Hauʻoli mākou e hoʻolaha aku e hoʻohana ʻia kēia lāʻau lapaʻau hou loa i nā poʻe maʻi ʻōpio e mālama ʻia ana i ka maʻi kanesa e pale aku i ka nalowale o ka lohe ma ke ʻano he hopena ʻaoʻao o ka chemotherapy cisplatin.
Ua hoʻomau ʻo Ralph: "Ke kakali nei mākou i ka ʻike ʻana i kēia lāʻau lapaʻau ma nā haukapila ma ka ʻāina a ke manaʻolana nei e loaʻa koke i nā keiki āpau e pōmaikaʻi mai ia mea ke komo i kēia lāʻau lapaʻau e hoʻōla ai i ke ola. Mahalo mākou i kā mākou poʻe kākoʻo no kā lākou hāʻawi ʻana, ka mea i hiki ai iā RNID ke hāʻawi iā NICE me nā manaʻo koʻikoʻi a me nā hōʻike e kōkua i ka loaʻa ʻana o kēia lāʻau lapaʻau ma ka UK. ʻO kēia ka manawa mua i hoʻomohala ʻia ai kahi lāʻau lapaʻau e pale aku i ka nalowale o ka lohe a ua ʻōlelo ʻia no ka hoʻohana ʻana ma ka NHS. He hanana koʻikoʻi kēia e hāʻawi i ka poʻe e hoʻopukapuka ana a me ka hoʻomohala ʻana i nā lāʻau lapaʻau no ka nalowale o ka lohe i ka hilinaʻi hiki iā lākou ke lawe maikaʻi i kahi lāʻau lapaʻau i ka mākeke. "
E loaʻa ka lāʻau lapaʻau ma ka NHS ma ʻEnelani i loko o ʻekolu mahina o ka hoʻopuka ʻia ʻana o ke alakaʻi hope loa a NICE.
Ua komo ka ʻoihana i loko o kahi ʻaelike kālepa malū e hoʻolako i ka sodium thiosulfate anhydrous i ka National Health Service ma ke kumu kūʻai i hoʻemi ʻia.